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The incredible power of the placenta

There are a lot of reasons to be excited about the month of July as it’s Cord Blood Awareness Month. Now a lot you may not be aware of the latest research on the subject but to put it simply, studies are showing that newborn stem cells can save lives and the primary source for these cells is from placenta tissue.

What are stem cells?

What are stem cells? Well, when a baby is born, some of its blood has superhero-like powers. Blood taken from its umbilical cord and placenta contains hematopoietic stem cells that can save lives. These cells replace other tissue in the body that don’t work correctly. Since this blood is so beneficial, many parents choose to keep it through stem cell banking services. We here at cellsave.ae offer such services.

What is the cord blood?

Cord blood is the blood inside the umbilical cord. Cord blood is valuable as a source of HSCa and MSCs. They can treat over 80 diseases, they proliferate, or reproduce, rapidly. They are biologically younger freezing them ‘stops the clock’ and protects them from being exposed to environmental damage, ageing and common viruses that can impact the stem cells in our bodies over time.

What is the cord tissue?

Cord tissue contains powerful and unique stem cells, including endothelial cells, epithelial cells and mesenchymal stem cells, which have the potential to repair and heal the body in different ways than cord blood stem cells do. Research on MSCs or mesenchymal stem cells shows great promise for regenerative practices. That is because these cells help the body reduce inflammation and repair damage to the tissue. Harnessing their ability to create structural and connective tissue, the stem cells contained in cord tissue are opening exciting new treatment opportunities for some of the world’s most devastating diseases. There are over 200 clinical trials initiated worldwide researching cord tissue stem cells in regenerative medicine for 6 therapeutic areas: autoimmune diseases, cardiovascular diseases, tissue or organ damage orthopedic Injuries, acquired neurological disorders and degenerative neurological disorders

What is placenta tissue?

The placenta is the tissue that develops during pregnancy. It is a unique temporary organ which ensures mutual coexistence of the organisms of mother and fetus, determining growth and development of the latter1. Since the placenta is a provisional organ, it becomes a salvage material after delivery 2. It’s made of mesenchymal stem cells, among other types of cells. Additionally, it transmits oxygen and nutrients from the mother to the child. It also gets rid of waste and harmful products from the child’s blood. For decades, clinicians and researchers work on the application of the placenta for therapeutic purposes, initially in the form of extracts and cell or tissue transplants, thus accumulating substantial empirical experience 3. As the tissue collects, it attaches to the uterus wall. Later the umbilical cord grows from the placenta. All of this tissue and placenta blood can help in stem cell research, and placental storage is a popular strategy to preserving this tissue.

What is amnion tissue?

The amnion tissue forms a membrane around the embryo. It adds a layer of protection. It also forms a sac that holds the amniotic fluid. That fluid keeps the embryo hydrated and also protects it from physical damage. Amniotic tissue has been used in clinical practice to a higher extent and mainly, it is used in surgery as a biological coating 4. The major applications include the closure of corneal pathology defects and treatment of nonhealing trophic ulcers, vaginal reconstruction surgery, enterocutaneous fistula, prevention of adhesions, orthopedic pathology, replacement of the pelvic peritoneum 5. Such application is determined by a range of unique properties of the amniotic membrane, such as transparency and the ability to stimulate proliferation and migration of stem cells from the limbus area, as well as the ability to suppress vascularization. This tissue can help medical research, which is why amnion tissue storage isso important.

Why are parents storing stem cells from these tissues?

From transplant medicine to regenerative medicine, scientists have spent years researching the benefits of these stem cells. There are a lot of possibilities and options. They can even help to treat leukemia and immune system diseases. If you decide to go with stem cell banking, you’re going to save lives. There is ongoing research in many different fields. Here are all the diseases you could help cure, and all the procedures you can help make a success.

Potential uses for the placenta and amnion tissue

1.   Ulcers

Diabetic foot ulcers are wounds that form on the skin but fail to heal over long periods of time. As a result of diabetes and high blood sugar, blood flow to the feet is restricted. So damaged nerves and cells have low rates of healing. In some experimental treatments, placenta cells are applied to the wound to speed up healing.

2.   Arthritis

Arthritis causes inflammation in the joints. Patients who suffer from this autoimmune disease have low responsive immunity systems and can suffer a loss of cartilage. At present, 23 clinical trials are studying the use of stem cells to treat arthritis. As well as, 24 studies looking into the use of cord blood.

3.   Stroke

Strokes are the third leading cause of mortality in the United States and the biggest cause of long-term disability. Often blood clots form in clogged arteries. The resulting inflammation can cause eventual brain damage. However, multiple recent studies link the use of placenta cells to effective treatment of this inflammation.

4.   Dry Eye

Dry eye affects 30 percent of all people. For those above the age of 60, the condition is as common as one in three. This happens when the body is not able to create tears. Current solutions involve eye drops with steroids. But these can have negative effects long-term. Research studies exploring the use of placenta and amnion tissue have shown promise.

5.   Burns

Burn injuries are painful and lower the quality of life for those injured. Skin grafts and surgery are the top two treatments patients seek out. However, the risks involve infections and blood loss. Traditional remedies have been using placenta and amnion tissue to treat burns for centuries. Recent medical research shows that these tissues help create new epithelial cells and prevent infection.

6.   Multiple Sclerosis

Multiple sclerosis impacts the brain and spinal cord. This autoimmune disease causes the body to attack the myelin. The myelin is meant to protect the central nervous system. A study by Dr. Fred Lubin showed that placenta cells could be used to help treat this condition.

7.   Transplantation

Organ transplants save the lives of thousands. However, there are risks involved. Patients often face complications, and the body may reject the new organ. Research studies conducted across the globe have shown that stem cells can increase the rate of successful transplants.

8.   Regenerative Medicine

This field of medicine looks into stem cells and how they can repair tissue. Blood taken from the placenta increases these stem cells. Preserving more stem cells means they may be used to treat more than one health condition that may affect your child or another close family member in the future.

How Cellsave can help you?

This brings us to Cellsave and the options we offer our clients. With our programs, you can protect your child’s health now and in the future. Our policies are flexible, and if you contact our customer care services, we can help you find the perfect plan. By saving your newborn’s stem cells, you ensure that your child and your family will have access to potential treatments. It never hurts to keep your options open. Especially in a field like stem cell research that shows new developments every year.

References:

(Vriesendorp H et al. Exp Hematol. 2016)(R. S. Yoshizawa, Placenta, vol. 34, no. 1, pp. 9–13, 2013)..(J. Zheng, In Tech, China, 2012; I. Kotomin, M. PLoS One, vol. 10, no. 5)(N. Koizumi et al. Ophthalmology, vol. 108, no. 9, pp. 1569–1574, 2001; N. Sharma et al. The British Journal of Ophthalmology, vol. 99, no. 5, pp. 669–673, 2015).(A. R. Silini et al. Frontiers in Bioengineering and Biotechnology, vol. 3, p. 162, 2015; J. C. Riboh et al. The American Journal of Sports Medicine, vol. 44, no. 9, pp. 2425–2434, 2016; I. Mermet et al. Wound Repair and Regeneration, vol. 15, no. 4,pp. 459–464, 2007; N. Heckmann et al. American Journal of Orthopedics, vol. 45, no. 7, pp. E421–E425, 2016).

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